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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Monomerid = 50263670   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50263670
PNG
(1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-...)
Show SMILES CC1CCCN(C1)c1ncnc2n(ncc12)-c1ccc(C)cc1C
Show InChI InChI=1/C19H23N5/c1-13-6-7-17(15(3)9-13)24-19-16(10-22-24)18(20-12-21-19)23-8-4-5-14(2)11-23/h6-7,9-10,12,14H,4-5,8,11H2,1-3H3
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.60E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at human mGluR4 expressed in CHO coexpressing Gqi5 assessed as potentiation of glutamate-induced calcium flux by fluorescence assay


Bioorg Med Chem Lett 18: 5626-30 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.087
BindingDB Entry DOI: 10.7270/Q24B327D
More data for this
Ligand-Target Pair