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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50265306   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50265306
PNG
(1-(4-(4-(2-(cyclohexylmethylamino)-5-nitrobenzoyl)...)
Show SMILES CC(=O)c1ccc(N2CCN(CC2)C(=O)c2cc(ccc2NCC2CCCCC2)[N+]([O-])=O)c(F)c1
Show InChI InChI=1S/C26H31FN4O4/c1-18(32)20-7-10-25(23(27)15-20)29-11-13-30(14-12-29)26(33)22-16-21(31(34)35)8-9-24(22)28-17-19-5-3-2-4-6-19/h7-10,15-16,19,28H,2-6,11-14,17H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in CHO cells by scintillation counter


Bioorg Med Chem Lett 18: 5134-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.086
BindingDB Entry DOI: 10.7270/Q28915PM
More data for this
Ligand-Target Pair