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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50265346   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50265346
PNG
(1-(4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)...)
Show SMILES CC(=O)c1ccc(N2CCN(CC2)C(=O)c2cc(ccc2OCC2CC2)S(C)(=O)=O)c(F)c1
Show InChI InChI=1S/C24H27FN2O5S/c1-16(28)18-5-7-22(21(25)13-18)26-9-11-27(12-10-26)24(29)20-14-19(33(2,30)31)6-8-23(20)32-15-17-3-4-17/h5-8,13-14,17H,3-4,9-12,15H2,1-2H3
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Similars

Article
PubMed
n/an/an/an/a 15n/an/an/an/a



F. Hoffmann-La Roche Inc

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in CHO cells by scintillation counter


Bioorg Med Chem Lett 18: 5134-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.086
BindingDB Entry DOI: 10.7270/Q28915PM
More data for this
Ligand-Target Pair