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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50266023   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50266023
PNG
(CHEMBL515659 | N-(benzo[c][1,2,5]oxadiazol-4-ylmet...)
Show SMILES CN1CCN(CC1)c1cnc2cc(cc(NCc3cccc4nonc34)c2n1)C(F)(F)F
Show InChI InChI=1S/C21H20F3N7O/c1-30-5-7-31(8-6-30)18-12-26-17-10-14(21(22,23)24)9-16(20(17)27-18)25-11-13-3-2-4-15-19(13)29-32-28-15/h2-4,9-10,12,25H,5-8,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 31n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50266023
PNG
(CHEMBL515659 | N-(benzo[c][1,2,5]oxadiazol-4-ylmet...)
Show SMILES CN1CCN(CC1)c1cnc2cc(cc(NCc3cccc4nonc34)c2n1)C(F)(F)F
Show InChI InChI=1S/C21H20F3N7O/c1-30-5-7-31(8-6-30)18-12-26-17-10-14(21(22,23)24)9-16(20(17)27-18)25-11-13-3-2-4-15-19(13)29-32-28-15/h2-4,9-10,12,25H,5-8,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 31n/an/an/an/an/an/a



UCB Celltech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant his-tagged c-Met by TR-FRET assay


Bioorg Med Chem Lett 19: 397-400 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.062
BindingDB Entry DOI: 10.7270/Q2ZC82QC
More data for this
Ligand-Target Pair