BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50267272   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50267272
PNG
(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Show SMILES CC(F)Cc1cc(C)cc(N)n1
Show InChI InChI=1S/C9H13FN2/c1-6-3-8(5-7(2)10)12-9(11)4-6/h3-4,7H,5H2,1-2H3,(H2,11,12)
PDB
MMDB

Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 490n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human recombinant nNOS using 1 mM NADH and 2 uM L-arginine after 30 mins


J Med Chem 52: 2443-53 (2009)


Article DOI: 10.1021/jm801556h
BindingDB Entry DOI: 10.7270/Q2QJ7H66
More data for this
Ligand-Target Pair