BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Monomerid = 50268781   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50268781
PNG
(1-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Show SMILES Cc1nc2c(NCc3c(C)cccc3C)cc(cn2c1C)-n1ccccc1=O
Show InChI InChI=1S/C23H24N4O/c1-15-8-7-9-16(2)20(15)13-24-21-12-19(26-11-6-5-10-22(26)28)14-27-18(4)17(3)25-23(21)27/h5-12,14,24H,13H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.70E+4n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6 (unknown origin)


Bioorg Med Chem Lett 19: 3602-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.127
BindingDB Entry DOI: 10.7270/Q2RX9BZV
More data for this
Ligand-Target Pair