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Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50271516   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50271516
PNG
(1-(4-(4-(trifluoromethyl)phenoxy)butyl)-1H-imidazo...)
Show SMILES FC(F)(F)c1ccc(OCCCCn2ccnc2)cc1
Show InChI InChI=1S/C14H15F3N2O/c15-14(16,17)12-3-5-13(6-4-12)20-10-2-1-8-19-9-7-18-11-19/h3-7,9,11H,1-2,8,10H2
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
9.40E+4n/an/an/an/an/an/an/an/a



Instituto de Química Médica

Curated by ChEMBL


Assay Description
Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrulline


Bioorg Med Chem 16: 6193-206 (2008)


Article DOI: 10.1016/j.bmc.2008.04.036
BindingDB Entry DOI: 10.7270/Q2611040
More data for this
Ligand-Target Pair