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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nitric Oxide Synthase, brain' and Monomerid = 50271651   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))
BDBM50271651
PNG
(CHEMBL483521 | N-Isobutyl-pyrazole-1-carboxamidine)
Show SMILES CC(C)CNC(=N)n1cccn1
Show InChI InChI=1S/C8H14N4/c1-7(2)6-10-8(9)12-5-3-4-11-12/h3-5,7H,6H2,1-2H3,(H2,9,10)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
4.50E+4n/an/an/an/an/an/an/an/a



Instituto de Química Médica

Curated by ChEMBL


Assay Description
Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrulline


Bioorg Med Chem 16: 6193-206 (2008)


Article DOI: 10.1016/j.bmc.2008.04.036
BindingDB Entry DOI: 10.7270/Q2611040
More data for this
Ligand-Target Pair