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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50272050   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50272050
PNG
(1-(4-(2-amino-3-(3-aminoprop-1-ynyl)pyridin-4-ylox...)
Show SMILES NCC#Cc1c(N)nccc1Oc1ccc(NC(=O)NC(=O)Cc2ccc(F)cc2)cc1F
Show InChI InChI=1S/C23H19F2N5O3/c24-15-5-3-14(4-6-15)12-21(31)30-23(32)29-16-7-8-20(18(25)13-16)33-19-9-11-28-22(27)17(19)2-1-10-26/h3-9,11,13H,10,12,26H2,(H2,27,28)(H2,29,30,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50272050
PNG
(1-(4-(2-amino-3-(3-aminoprop-1-ynyl)pyridin-4-ylox...)
Show SMILES NCC#Cc1c(N)nccc1Oc1ccc(NC(=O)NC(=O)Cc2ccc(F)cc2)cc1F
Show InChI InChI=1S/C23H19F2N5O3/c24-15-5-3-14(4-6-15)12-21(31)30-23(32)29-16-7-8-20(18(25)13-16)33-19-9-11-28-22(27)17(19)2-1-10-26/h3-9,11,13H,10,12,26H2,(H2,27,28)(H2,29,30,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of Met kinase (unknown origin)


Bioorg Med Chem Lett 18: 3224-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.047
BindingDB Entry DOI: 10.7270/Q2XG9QX1
More data for this
Ligand-Target Pair