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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-3 Adrenergic Receptor' and Monomerid = 50273246   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50273246
PNG
(4-((7S)-7-{[(2R)-2-(4-Chlorophenyl)-2-hydroxyethyl...)
Show SMILES Cc1cc(ccc1-c1ccc2CC[C@@H](Cc2c1)NC[C@H](O)c1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C26H26ClNO3/c1-16-12-20(26(30)31)7-11-24(16)19-3-2-17-6-10-23(14-21(17)13-19)28-15-25(29)18-4-8-22(27)9-5-18/h2-5,7-9,11-13,23,25,28-29H,6,10,14-15H2,1H3,(H,30,31)/t23-,25-/m0/s1
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Similars

Article
PubMed
n/an/an/an/a 2n/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation


J Med Chem 51: 4804-22 (2008)


Article DOI: 10.1021/jm800222k
BindingDB Entry DOI: 10.7270/Q25D8SQ8
More data for this
Ligand-Target Pair