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Found 2 Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50273389
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273389(2-(4-Chloro-6-(4'-cyanobiphenyl-4-ylamino)pyrimidi...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 5-LO in PMNL cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273389(2-(4-Chloro-6-(4'-cyanobiphenyl-4-ylamino)pyrimidi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli by cell-free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed