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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 9A' and Monomerid = 50273601   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50273601
PNG
(4-[3-Methoxy-4-(pyridin-2-yloxy)phenyl]-4-quinolin...)
Show SMILES COc1cc(ccc1Oc1ccccn1)C(CC(C)=O)c1cnc2ccccc2c1
Show InChI InChI=1/C25H22N2O3/c1-17(28)13-21(20-14-19-7-3-4-8-22(19)27-16-20)18-10-11-23(24(15-18)29-2)30-25-9-5-6-12-26-25/h3-12,14-16,21H,13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of human cloned PDE9A2 expressed in Escherichia coli BL21 by liquid scintillation counting


J Med Chem 51: 7673-88 (2008)


Article DOI: 10.1021/jm701635j
BindingDB Entry DOI: 10.7270/Q2736QRN
More data for this
Ligand-Target Pair