BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 9A' and Monomerid = 50273983   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50273983
PNG
(1-[3-Methoxy-4-(pyridin-2-yloxy)phenyl]-1-quinolin...)
Show SMILES CCCC(O)(c1ccc(Oc2ccccn2)c(OC)c1)c1cnc2ccccc2c1
Show InChI InChI=1/C25H24N2O3/c1-3-13-25(28,20-15-18-8-4-5-9-21(18)27-17-20)19-11-12-22(23(16-19)29-2)30-24-10-6-7-14-26-24/h4-12,14-17,28H,3,13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Georgia State University

Curated by ChEMBL


Assay Description
Inhibition of human cloned PDE9A2 expressed in Escherichia coli BL21 by liquid scintillation counting


J Med Chem 51: 7673-88 (2008)


Article DOI: 10.1021/jm701635j
BindingDB Entry DOI: 10.7270/Q2736QRN
More data for this
Ligand-Target Pair