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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine transporter 1' and Monomerid = 50277757   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50277757
PNG
(2,4-dichloro-N-((1-(cyclopropylmethylsulfonyl)-4-(...)
Show SMILES Fc1cccnc1C1(CNC(=O)c2ccc(Cl)cc2Cl)CCN(CC1)S(=O)(=O)CC1CC1
Show InChI InChI=1S/C22H24Cl2FN3O3S/c23-16-5-6-17(18(24)12-16)21(29)27-14-22(20-19(25)2-1-9-26-20)7-10-28(11-8-22)32(30,31)13-15-3-4-15/h1-2,5-6,9,12,15H,3-4,7-8,10-11,13-14H2,(H,27,29)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Merck Sharp and Dohme

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation counting


Bioorg Med Chem Lett 19: 2235-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.102
BindingDB Entry DOI: 10.7270/Q23R0SSZ
More data for this
Ligand-Target Pair