Found 7 Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 7A' and Monomerid = 50277784 TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]-cAMP from recombinant human PDE7A1 incubated for 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human PDE7A using cAMP as substrate after 10 mins by PDE-Glo Phosphodiesterase AssayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human recombinant PDE7A using cAMP as substrate incubated for 20 mins measured by Kinase Glo reagent based microplate reader assayMore data for this Ligand-Target Pair
