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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50277915   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50277915
PNG
((R)-3-((3'-chlorobiphenyl-4-yl)methyl)-5-methyloxa...)
Show SMILES C[C@@H]1CN(Cc2ccc(cc2)-c2cccc(Cl)c2)C(=O)O1
Show InChI InChI=1S/C17H16ClNO2/c1-12-10-19(17(20)21-12)11-13-5-7-14(8-6-13)15-3-2-4-16(18)9-15/h2-9,12H,10-11H2,1H3/t12-/m1/s1
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Article
PubMed
n/an/an/an/a 158n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate


Bioorg Med Chem Lett 19: 2524-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.032
BindingDB Entry DOI: 10.7270/Q2F18ZK7
More data for this
Ligand-Target Pair