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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Monomerid = 50277918   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50277918
PNG
((R)-3-((3'-methoxybiphenyl-4-yl)methyl)-5-methylox...)
Show SMILES COc1cccc(c1)-c1ccc(CN2C[C@@H](C)OC2=O)cc1
Show InChI InChI=1S/C18H19NO3/c1-13-11-19(18(20)22-13)12-14-6-8-15(9-7-14)16-4-3-5-17(10-16)21-2/h3-10,13H,11-12H2,1-2H3/t13-/m1/s1
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Similars

Article
PubMed
n/an/an/an/a 275n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate


Bioorg Med Chem Lett 19: 2524-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.032
BindingDB Entry DOI: 10.7270/Q2F18ZK7
More data for this
Ligand-Target Pair