BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50280179   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (human))
BDBM50280179
PNG
(1-(3-Hydroxymethyl-phenyl)-tetrahydro-pyridazin-3-...)
Show SMILES OCc1cccc(c1)N1CCCC(=O)N1
Show InChI InChI=1S/C11H14N2O2/c14-8-9-3-1-4-10(7-9)13-6-2-5-11(15)12-13/h1,3-4,7,14H,2,5-6,8H2,(H,12,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 5.30E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-lipoxygenase.


Bioorg Med Chem Lett 2: 1357-1360 (1992)


Article DOI: 10.1016/S0960-894X(00)80512-0
BindingDB Entry DOI: 10.7270/Q2CC10M8
More data for this
Ligand-Target Pair