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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Lipoxygenase' and Monomerid = 50280967   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50280967
PNG
(5-Benzo[1,3]dioxol-5-yl-5,9-dihydro-furo[3',4':6,7...)
Show SMILES C1Oc2ccc(cc2O1)C1c2cocc2Cc2cc3OCOc3cc12
Show InChI InChI=1S/C20H14O5/c1-2-16-17(23-9-22-16)4-11(1)20-14-6-19-18(24-10-25-19)5-12(14)3-13-7-21-8-15(13)20/h1-2,4-8,20H,3,9-10H2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
n/an/a 420n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated in vitro for inhibition of LTB4 biosynthesis by human leukocytes


Bioorg Med Chem Lett 3: 2063-2066 (1993)


Article DOI: 10.1016/S0960-894X(01)81016-7
BindingDB Entry DOI: 10.7270/Q2T43T1Z
More data for this
Ligand-Target Pair