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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Monomerid = 50286905   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))
BDBM50286905
PNG
((S)-5-Biphenyl-4-yl-4-(1-carboxy-ethylcarbamoyl)-2...)
Show SMILES CC(NC(=O)[C@@H](CC(COc1ccccc1)C(O)=O)Cc1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C28H29NO6/c1-19(27(31)32)29-26(30)23(17-24(28(33)34)18-35-25-10-6-3-7-11-25)16-20-12-14-22(15-13-20)21-8-4-2-5-9-21/h2-15,19,23-24H,16-18H2,1H3,(H,29,30)(H,31,32)(H,33,34)/t19?,23-,24?/m1/s1
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Similars

Article
n/an/a 2.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of neutral endopeptidase from rat kidney.


Bioorg Med Chem Lett 6: 65-70 (1996)


Article DOI: 10.1016/0960-894X(95)00551-4
BindingDB Entry DOI: 10.7270/Q2BZ66J9
More data for this
Ligand-Target Pair