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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Monomerid = 50286908   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Homo sapiens (Human))
BDBM50286908
PNG
((2R,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Show SMILES OC(=O)CNC(=O)[C@@H](C[C@H](COc1ccccc1)C(O)=O)Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c29-25(30)17-28-26(31)22(16-23(27(32)33)18-34-24-9-5-2-6-10-24)15-19-11-13-21(14-12-19)20-7-3-1-4-8-20/h1-14,22-23H,15-18H2,(H,28,31)(H,29,30)(H,32,33)/t22-,23-/m1/s1
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Similars

Article
n/an/a 5.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of Neutral Endopeptidase


Bioorg Med Chem Lett 6: 1487-1490 (1996)


Article DOI: 10.1016/S0960-894X(96)00255-7
BindingDB Entry DOI: 10.7270/Q2B27VSQ
More data for this
Ligand-Target Pair