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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Excitatory amino acid transporter 1' and Monomerid = 50293004   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Excitatory amino acid transporter 1


(Homo sapiens (Human))
BDBM50293004
PNG
(2-amino-4-(4-bromothiophen-2-yl)-5-oxo-7-phenyl-5,...)
Show SMILES Brc1csc(c1)C1C(C#N)C(=N)OC2=C1C(=O)CC(C2)c1ccccc1
Show InChI InChI=1/C20H15BrN2O2S/c21-13-8-17(26-10-13)18-14(9-22)20(23)25-16-7-12(6-15(24)19(16)18)11-4-2-1-3-5-11/h1-5,8,10,12,14,18,23H,6-7H2
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Displacement of [3H]D-Asp from human EAAT1 receptor expressed in HEK293 cells


J Med Chem 52: 912-5 (2009)


Article DOI: 10.1021/jm8013458
BindingDB Entry DOI: 10.7270/Q2PV6KCP
More data for this
Ligand-Target Pair