Found 2 Enz. Inhib. hit(s) with Target = 'ATP-Binding Cassette Transporter ABCG2' and Monomerid = 50293013
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional De Colombia
Curated by ChEMBL
Universidad Nacional De Colombia
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional De Colombia
Curated by ChEMBL
Universidad Nacional De Colombia
Curated by ChEMBL
Affinity DataIC50: 179nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair