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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-1 Adrenergic Receptor' and Monomerid = 50293419   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-1 adrenergic receptor


(Homo sapiens (human))
BDBM50293419
PNG
((S)-4'-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]a...)
Show SMILES O[C@@H](CNCCc1ccc(NC(=O)Cc2ccc(Cl)cc2)cc1)COc1ccc(O)cc1
Show InChI InChI=1S/C25H27ClN2O4/c26-20-5-1-19(2-6-20)15-25(31)28-21-7-3-18(4-8-21)13-14-27-16-23(30)17-32-24-11-9-22(29)10-12-24/h1-12,23,27,29-30H,13-17H2,(H,28,31)/t23-/m0/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 190n/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as increase in cAMP production after 2 days by radioimmun...


Eur J Med Chem 44: 2533-43 (2009)


Article DOI: 10.1016/j.ejmech.2009.01.022
BindingDB Entry DOI: 10.7270/Q2JM2BJV
More data for this
Ligand-Target Pair