Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50293641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50293641 (6-Phenylethynyl-nicotinamide | CHEMBL561554) Show SMILES NC(=O)c1ccc(nc1)C#Cc1ccccc1 Show InChI InChI=1S/C14H10N2O/c15-14(17)12-7-9-13(16-10-12)8-6-11-4-2-1-3-5-11/h1-5,7,9-10H,(H2,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assay				Bioorg Med Chem Lett 19: 3275-8 (2009) Article DOI: 10.1016/j.bmcl.2009.04.095 BindingDB Entry DOI: 10.7270/Q2J1035D
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