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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50293641   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50293641
PNG
(6-Phenylethynyl-nicotinamide | CHEMBL561554)
Show SMILES NC(=O)c1ccc(nc1)C#Cc1ccccc1
Show InChI InChI=1S/C14H10N2O/c15-14(17)12-7-9-13(16-10-12)8-6-11-4-2-1-3-5-11/h1-5,7,9-10H,(H2,15,17)
PDB
MMDB

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Similars

Article
PubMed
n/an/an/an/a 6.60E+3n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assay


Bioorg Med Chem Lett 19: 3275-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.095
BindingDB Entry DOI: 10.7270/Q2J1035D
More data for this
Ligand-Target Pair