BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50293642   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50293642
PNG
(CHEMBL551957 | N-isopentyl-6-(2-phenylethynyl)nico...)
Show SMILES CC(C)CCNC(=O)c1ccc(nc1)C#Cc1ccccc1
Show InChI InChI=1S/C19H20N2O/c1-15(2)12-13-20-19(22)17-9-11-18(21-14-17)10-8-16-6-4-3-5-7-16/h3-7,9,11,14-15H,12-13H2,1-2H3,(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 510n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assay


Bioorg Med Chem Lett 19: 3275-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.095
BindingDB Entry DOI: 10.7270/Q2J1035D
More data for this
Ligand-Target Pair