BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50293646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50293646
PNG
(CHEMBL551894 | N-(furan-2-ylmethyl)-6-(phenylethyn...)
Show SMILES O=C(NCc1ccco1)c1ccc(nc1)C#Cc1ccccc1
Show InChI InChI=1S/C19H14N2O2/c22-19(21-14-18-7-4-12-23-18)16-9-11-17(20-13-16)10-8-15-5-2-1-3-6-15/h1-7,9,11-13H,14H2,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 180n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assay


Bioorg Med Chem Lett 19: 3275-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.095
BindingDB Entry DOI: 10.7270/Q2J1035D
More data for this
Ligand-Target Pair