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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50293653   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50293653
PNG
((4-methylpiperazin-1-yl)(6-(2-phenylethynyl)pyridi...)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(nc1)C#Cc1ccccc1
Show InChI InChI=1S/C19H19N3O/c1-21-11-13-22(14-12-21)19(23)17-8-10-18(20-15-17)9-7-16-5-3-2-4-6-16/h2-6,8,10,15H,11-14H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.60E+3n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assay


Bioorg Med Chem Lett 19: 3275-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.095
BindingDB Entry DOI: 10.7270/Q2J1035D
More data for this
Ligand-Target Pair