BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Monomerid = 50295529   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2D6 (2D6)


(Homo sapiens (Human))
BDBM50295529
PNG
(CHEMBL563732 | N-(2-phenylcyclopropyl)-4-(1H-1,2,4...)
Show SMILES O=C(NC1CC1c1ccccc1)N1CCC(CC1)n1cncn1
Show InChI InChI=1S/C17H21N5O/c23-17(20-16-10-15(16)13-4-2-1-3-5-13)21-8-6-14(7-9-21)22-12-18-11-19-22/h1-5,11-12,14-16H,6-10H2,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CYP2D6


J Med Chem 52: 5009-12 (2010)


Article DOI: 10.1021/jm900725r
BindingDB Entry DOI: 10.7270/Q2TX3G8W
More data for this
Ligand-Target Pair