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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50295731   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50295731
PNG
(1-(2,3-dichlorophenylsulfonyl)-1H-pyrrolo[3,2-b]py...)
Show SMILES Clc1cccc(c1Cl)S(=O)(=O)n1ccc2ncccc12
Show InChI InChI=1S/C13H8Cl2N2O2S/c14-9-3-1-5-12(13(9)15)20(18,19)17-8-6-10-11(17)4-2-7-16-10/h1-8H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50295731
PNG
(1-(2,3-dichlorophenylsulfonyl)-1H-pyrrolo[3,2-b]py...)
Show SMILES Clc1cccc(c1Cl)S(=O)(=O)n1ccc2ncccc12
Show InChI InChI=1S/C13H8Cl2N2O2S/c14-9-3-1-5-12(13(9)15)20(18,19)17-8-6-10-11(17)4-2-7-16-10/h1-8H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



UCB Celltech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged c-Met by TR-FRET assay


Bioorg Med Chem Lett 19: 2780-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.110
BindingDB Entry DOI: 10.7270/Q2BV7GN9
More data for this
Ligand-Target Pair