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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epoxide hydratase' and Monomerid = 50296223   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epoxide hydratase


(Homo sapiens (Human))
BDBM50296223
PNG
(1-(4-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(OCCCN3CCOCC3)cc2)cc1
Show InChI InChI=1S/C21H24F3N3O3/c22-21(23,24)16-2-4-17(5-3-16)25-20(28)26-18-6-8-19(9-7-18)30-13-1-10-27-11-14-29-15-12-27/h2-9H,1,10-15H2,(H2,25,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.800n/an/an/an/an/an/a



Arete Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assay


Bioorg Med Chem Lett 19: 4259-63 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.102
BindingDB Entry DOI: 10.7270/Q2VQ32Q0
More data for this
Ligand-Target Pair