Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50296666
TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296666(3-(2-chloro-6-methylquinolin-3-yl)-1-(thiophen-2-y...)
Affinity DataKi:  9.93E+3nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296666(3-(2-chloro-6-methylquinolin-3-yl)-1-(thiophen-2-y...)
Affinity DataIC50:  740nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed