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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50296695
TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296695(CHEMBL537963 | N-((9-ethyl-9H-carbazol-3-yl)methyl...)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296695(CHEMBL537963 | N-((9-ethyl-9H-carbazol-3-yl)methyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed