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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Monomerid = 50297127   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50297127
PNG
(CHEMBL564842 | endo-1-(3-(8-methyl-8-azabicyclo[3....)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(CC(CNC(N)=O)(c1ccccc1)c1ccccc1)C2
Show InChI InChI=1S/C24H31N3O/c1-27-21-12-13-22(27)15-18(14-21)16-24(17-26-23(25)28,19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-11,18,21-22H,12-17H2,1H3,(H3,25,26,28)/t21-,22-/m1/s1
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Similars

Article
PubMed
n/an/a 6.40E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...


Bioorg Med Chem Lett 19: 4560-2 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.006
BindingDB Entry DOI: 10.7270/Q2DB81WW
More data for this
Ligand-Target Pair