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Found 1 hit Enz. Inhib. hit(s) with Target = 'Telomerase reverse transcriptase' and Monomerid = 50298371   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50298371
PNG
(2,2'-[4,5-Acridindiylbis(methyleneimino)]bis(N,N,N...)
Show SMILES C[N+](C)(C)CCC(=O)NCc1cccc2cc3cccc(CNC(=O)CC[N+](C)(C)C)c3nc12
Show InChI InChI=1S/C27H37N5O2/c1-31(2,3)15-13-24(33)28-18-22-11-7-9-20-17-21-10-8-12-23(27(21)30-26(20)22)19-29-25(34)14-16-32(4,5)6/h7-12,17H,13-16,18-19H2,1-6H3/p+2
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Universit£ de Reims Champagne-Ardenne

Curated by ChEMBL


Assay Description
Inhibition of human telomerase in A549 cells by TRAP assay


Eur J Med Chem 44: 3880-8 (2009)


Article DOI: 10.1016/j.ejmech.2009.04.021
BindingDB Entry DOI: 10.7270/Q2W37WDH
More data for this
Ligand-Target Pair