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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50299273   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50299273
PNG
((R)-4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N...)
Show SMILES Nc1ncc(nc1Oc1ccc2cc[nH]c2c1)-c1ccc(cc1)C(=O)N[C@@H]1CCNC1
Show InChI InChI=1S/C23H22N6O2/c24-21-23(31-18-6-5-15-7-10-26-19(15)11-18)29-20(13-27-21)14-1-3-16(4-2-14)22(30)28-17-8-9-25-12-17/h1-7,10-11,13,17,25-26H,8-9,12H2,(H2,24,27)(H,28,30)/t17-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.37E+4n/an/an/an/an/an/a



Eli Lilly and Company Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of recombinant MET by [gamma-33-P]-ATP based assay


J Med Chem 52: 6456-66 (2009)


Article DOI: 10.1021/jm901147e
BindingDB Entry DOI: 10.7270/Q2TX3FFQ
More data for this
Ligand-Target Pair