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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50299276   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50299276
PNG
(4-(5-amino-6-(1-(2,6-dichlorophenyl)ethoxy)pyrazin...)
Show SMILES CC(Oc1nc(cnc1N)-c1ccc(cc1)C(=O)NCC1CCCNC1)c1c(Cl)cccc1Cl
Show InChI InChI=1/C25H27Cl2N5O2/c1-15(22-19(26)5-2-6-20(22)27)34-25-23(28)30-14-21(32-25)17-7-9-18(10-8-17)24(33)31-13-16-4-3-11-29-12-16/h2,5-10,14-16,29H,3-4,11-13H2,1H3,(H2,28,30)(H,31,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.21E+3n/an/an/an/an/an/a



Eli Lilly and Company Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of recombinant MET by [gamma-33-P]-ATP based assay


J Med Chem 52: 6456-66 (2009)


Article DOI: 10.1021/jm901147e
BindingDB Entry DOI: 10.7270/Q2TX3FFQ
More data for this
Ligand-Target Pair