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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50299755   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50299755
PNG
(CHEMBL574864 | N-(4-(6,7-dimethoxyquinolin-4-yloxy...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccc(F)cc4)cc3F)c2cc1OC
Show InChI InChI=1S/C27H22F2N4O5/c1-36-24-14-19-21(15-25(24)37-2)30-10-9-22(19)38-23-8-5-17(13-20(23)29)31-26(34)33-12-11-32(27(33)35)18-6-3-16(28)4-7-18/h3-10,13-15H,11-12H2,1-2H3,(H,31,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged c-Met expressed in Sf9 cells


Bioorg Med Chem Lett 19: 6552-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.040
BindingDB Entry DOI: 10.7270/Q2VM4D6R
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50299755
PNG
(CHEMBL574864 | N-(4-(6,7-dimethoxyquinolin-4-yloxy...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccc(F)cc4)cc3F)c2cc1OC
Show InChI InChI=1S/C27H22F2N4O5/c1-36-24-14-19-21(15-25(24)37-2)30-10-9-22(19)38-23-8-5-17(13-20(23)29)31-26(34)33-12-11-32(27(33)35)18-6-3-16(28)4-7-18/h3-10,13-15H,11-12H2,1-2H3,(H,31,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 90n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of TPR-Met assessed as autophosphorylation


Bioorg Med Chem Lett 19: 6552-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.040
BindingDB Entry DOI: 10.7270/Q2VM4D6R
More data for this
Ligand-Target Pair