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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Monomerid = 50299756   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50299756
PNG
(CHEMBL576769 | N-(4-(6,7-dimethoxyquinolin-4-yloxy...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)c(F)c3)c2cc1OC
Show InChI InChI=1S/C27H23FN4O5/c1-35-24-15-19-22(16-25(24)36-2)29-11-10-23(19)37-18-8-9-21(20(28)14-18)30-26(33)32-13-12-31(27(32)34)17-6-4-3-5-7-17/h3-11,14-16H,12-13H2,1-2H3,(H,30,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged c-Met expressed in Sf9 cells


Bioorg Med Chem Lett 19: 6552-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.040
BindingDB Entry DOI: 10.7270/Q2VM4D6R
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50299756
PNG
(CHEMBL576769 | N-(4-(6,7-dimethoxyquinolin-4-yloxy...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)c(F)c3)c2cc1OC
Show InChI InChI=1S/C27H23FN4O5/c1-35-24-15-19-22(16-25(24)36-2)29-11-10-23(19)37-18-8-9-21(20(28)14-18)30-26(33)32-13-12-31(27(32)34)17-6-4-3-5-7-17/h3-11,14-16H,12-13H2,1-2H3,(H,30,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of TPR-Met assessed as autophosphorylation


Bioorg Med Chem Lett 19: 6552-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.040
BindingDB Entry DOI: 10.7270/Q2VM4D6R
More data for this
Ligand-Target Pair