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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphodiesterase 6A' and Monomerid = 50300987   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 6A


(Homo sapiens (Human))
BDBM50300987
PNG
(3-(3-hydroxypropylamino)-7-(6-methoxypyridin-3-yl)...)
Show SMILES CCCOCCn1c2cc(ncc2nc(NCCCO)c1=O)-c1ccc(OC)nc1
Show InChI InChI=1S/C21H27N5O4/c1-3-10-30-11-8-26-18-12-16(15-5-6-19(29-2)24-13-15)23-14-17(18)25-20(21(26)28)22-7-4-9-27/h5-6,12-14,27H,3-4,7-11H2,1-2H3,(H,22,25)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of PDE6


Bioorg Med Chem Lett 19: 5209-13 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.019
BindingDB Entry DOI: 10.7270/Q2H41RHV
More data for this
Ligand-Target Pair