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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Monomerid = 50301526   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50301526
PNG
(CHEMBL576043 | N-methyl-N-(4-(pyridin-4-yl)thiazol...)
Show SMILES CN(C(=O)c1ccc(OC(F)(F)F)cc1)c1nc(cs1)-c1ccncc1
Show InChI InChI=1S/C17H12F3N3O2S/c1-23(16-22-14(10-26-16)11-6-8-21-9-7-11)15(24)12-2-4-13(5-3-12)25-17(18,19)20/h2-10H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR1 receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 5464-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.097
BindingDB Entry DOI: 10.7270/Q2W66KTT
More data for this
Ligand-Target Pair