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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50301976   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50301976
PNG
(2-(6-(4-amino-3'-(aminomethyl)biphenyl-3-yloxy)-3,...)
Show SMILES Cc1ccc(C(O)=O)c(Oc2nc(Oc3cc(ccc3N)-c3cccc(CN)c3)c(F)cc2F)c1
Show InChI InChI=1S/C26H21F2N3O4/c1-14-5-7-18(26(32)33)22(9-14)34-24-19(27)12-20(28)25(31-24)35-23-11-17(6-8-21(23)30)16-4-2-3-15(10-16)13-29/h2-12H,13,29-30H2,1H3,(H,32,33)
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n/an/a 89n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of uPA


Bioorg Med Chem Lett 19: 5712-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.008
BindingDB Entry DOI: 10.7270/Q2JQ113Z
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50301976
PNG
(2-(6-(4-amino-3'-(aminomethyl)biphenyl-3-yloxy)-3,...)
Show SMILES Cc1ccc(C(O)=O)c(Oc2nc(Oc3cc(ccc3N)-c3cccc(CN)c3)c(F)cc2F)c1
Show InChI InChI=1S/C26H21F2N3O4/c1-14-5-7-18(26(32)33)22(9-14)34-24-19(27)12-20(28)25(31-24)35-23-11-17(6-8-21(23)30)16-4-2-3-15(10-16)13-29/h2-12H,13,29-30H2,1H3,(H,32,33)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of plasmin


Bioorg Med Chem Lett 19: 5712-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.008
BindingDB Entry DOI: 10.7270/Q2JQ113Z
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50301976
PNG
(2-(6-(4-amino-3'-(aminomethyl)biphenyl-3-yloxy)-3,...)
Show SMILES Cc1ccc(C(O)=O)c(Oc2nc(Oc3cc(ccc3N)-c3cccc(CN)c3)c(F)cc2F)c1
Show InChI InChI=1S/C26H21F2N3O4/c1-14-5-7-18(26(32)33)22(9-14)34-24-19(27)12-20(28)25(31-24)35-23-11-17(6-8-21(23)30)16-4-2-3-15(10-16)13-29/h2-12H,13,29-30H2,1H3,(H,32,33)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of tPA


Bioorg Med Chem Lett 19: 5712-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.008
BindingDB Entry DOI: 10.7270/Q2JQ113Z
More data for this
Ligand-Target Pair