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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Plasmin' and Monomerid = 50301981   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50301981
PNG
(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Show SMILES NCc1cccc(c1)-c1cccc(Oc2nc(Oc3ccccc3C(O)=O)c(F)cc2F)c1
Show InChI InChI=1S/C25H18F2N2O4/c26-20-13-21(27)24(33-22-10-2-1-9-19(22)25(30)31)29-23(20)32-18-8-4-7-17(12-18)16-6-3-5-15(11-16)14-28/h1-13H,14,28H2,(H,30,31)
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PubMed
n/an/a 840n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of uPA


Bioorg Med Chem Lett 19: 5712-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.008
BindingDB Entry DOI: 10.7270/Q2JQ113Z
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50301981
PNG
(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Show SMILES NCc1cccc(c1)-c1cccc(Oc2nc(Oc3ccccc3C(O)=O)c(F)cc2F)c1
Show InChI InChI=1S/C25H18F2N2O4/c26-20-13-21(27)24(33-22-10-2-1-9-19(22)25(30)31)29-23(20)32-18-8-4-7-17(12-18)16-6-3-5-15(11-16)14-28/h1-13H,14,28H2,(H,30,31)
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n/an/a 2.10E+4n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of plasmin


Bioorg Med Chem Lett 19: 5712-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.008
BindingDB Entry DOI: 10.7270/Q2JQ113Z
More data for this
Ligand-Target Pair
Tissue-type plasminogen activator


(Homo sapiens (Human))
BDBM50301981
PNG
(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Show SMILES NCc1cccc(c1)-c1cccc(Oc2nc(Oc3ccccc3C(O)=O)c(F)cc2F)c1
Show InChI InChI=1S/C25H18F2N2O4/c26-20-13-21(27)24(33-22-10-2-1-9-19(22)25(30)31)29-23(20)32-18-8-4-7-17(12-18)16-6-3-5-15(11-16)14-28/h1-13H,14,28H2,(H,30,31)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Berlex Biosciences

Curated by ChEMBL


Assay Description
Inhibition of tPA


Bioorg Med Chem Lett 19: 5712-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.008
BindingDB Entry DOI: 10.7270/Q2JQ113Z
More data for this
Ligand-Target Pair