Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Monomerid = 50302905
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302905(7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302905(7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human CYP3A4 in human liver microsomes preincubated with NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302905(7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302905(7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed