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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Monomerid = 50303070
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303070((R)-3-(6-(1-(4-fluorophenyl)ethylamino)pyrimidin-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303070((R)-3-(6-(1-(4-fluorophenyl)ethylamino)pyrimidin-4...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human HT2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed