Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Monomerid = 50303815
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303815((R)-2-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataKi:  4.30nMAssay Description:Displacement of GS-red from human glucocorticoid receptor by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303815((R)-2-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataEC50:  57nMAssay Description:Transrepression activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of PMA-induced AP1 activity after 6 hrs by l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303815((R)-2-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataEC50:  79nMAssay Description:Transrepression activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of IL-1-beta-induced NF-kappaB dependent E-s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50303815((R)-2-((5aR,6S)-1-(4-Fluorophenyl)-5a-methyl-5,5a,...)
Affinity DataEC50: >5.00E+3nMAssay Description:Transactivation of GAL-4 tagged glucocorticoid receptor ligand binding domain expressed in human HeLa cells assessed as NP1 activation by luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed