Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Monomerid = 50305045
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305045(CHEMBL594295 | rac-(5-chloro-6-(6-methylpyridin-3-...)
Affinity DataIC50:  105nMAssay Description:Antagonist activity at human mGluR5 assessed as inhibition of glutamate-induced elevation of intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305045(CHEMBL594295 | rac-(5-chloro-6-(6-methylpyridin-3-...)
Affinity DataIC50:  310nMAssay Description:Antagonist activity at human mGluR5 assessed as inhibition of quisqualate-induced intracellular inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed