BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase receptor FLT3' and Monomerid = 50306683   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50306683
PNG
((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Show SMILES C[C@@H](Oc1ccc2ncccc2c1)c1c(Cl)ccc(F)c1Cl
Show InChI InChI=1S/C17H12Cl2FNO/c1-10(16-13(18)5-6-14(20)17(16)19)22-12-4-7-15-11(9-12)3-2-8-21-15/h2-10H,1H3/t10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.60E+4n/an/an/an/an/an/a



Chugai Pharmaceutical Co, Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant Flt3 by TR-FRET assay


Bioorg Med Chem Lett 20: 1405-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.109
BindingDB Entry DOI: 10.7270/Q2HQ401G
More data for this
Ligand-Target Pair