Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 3A4' and Monomerid = 50310823
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310823(CHEMBL1078442 | bergamottin)
Affinity DataKi:  7.70E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 3A4 measured by testosterone 6-beta hydroxylation and erythromycin N-demethylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50310823(CHEMBL1078442 | bergamottin)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed