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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclooxygenase-1' and Monomerid = 50311376   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-1 (COX-1)


(Homo sapiens (Human))
BDBM50311376
PNG
(CHEMBL1078377 | N-[3-(2-ethylphenylamino)-4-pyridi...)
Show SMILES CCc1ccccc1Nc1cnccc1NS(C)(=O)=O
Show InChI InChI=1S/C14H17N3O2S/c1-3-11-6-4-5-7-12(11)16-14-10-15-9-8-13(14)17-20(2,18)19/h4-10,16H,3H2,1-2H3,(H,15,17)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.79E+3n/an/an/an/an/an/a



University of Liege

Curated by ChEMBL


Assay Description
Inhibition of COX1 in human whole blood assessed as TXB2 production by enzyme immunoassay


J Med Chem 52: 5864-71 (2009)


Article DOI: 10.1021/jm900702b
BindingDB Entry DOI: 10.7270/Q2CV4JQ6
More data for this
Ligand-Target Pair